Is the Nucleus ASIO driver multiclient? February 09, 2019 08:09 Is the Nucleus ASIO driver multiclient?Yes it is. Multiple ASIO applications are able to utilise the ASIO driver simultaneously. Related articles What is the power consumption of the Nucleus? Why do I have only one-way communication between Pro Tools (on PC) and the Nucleus control surface? Nucleus on Windows IpMIDI Loopback Nucleus USB Soundcard v3 Driver How does Nucleus control my DAW?