The Matrix can be used with DAW software that conforms to the MCU or HUI control surface protocols. The mapping of physical Matrix controls to DAW software functions is determined by the selected 'profile'.
Matrix comes with default profiles for Apple Logic Pro, Digidesign ProTools and Steinberg Cubase/Nuendo. Profiles for Ableton Live and Propellorhead Reason are available for download from:
For more information on the default profiles and on how to create your own please see Chapter 6 of the Matrix Owner's Manual.